A comparison of CA125, HE4, risk ovarian malignancy algorithm (ROMA), and risk malignancy index (RMI) for the classification of ovarian masses
نویسندگان
چکیده
منابع مشابه
A comparison of CA125, HE4, risk ovarian malignancy algorithm (ROMA), and risk malignancy index (RMI) for the classification of ovarian masses
OBJECTIVE Differentiation between benign and malignant ovarian neoplasms is essential for creating a system for patient referrals. Therefore, the contributions of the tumor markers CA125 and human epididymis protein 4 (HE4) as well as the risk ovarian malignancy algorithm (ROMA) and risk malignancy index (RMI) values were considered individually and in combination to evaluate their utility for ...
متن کاملEvaluation of diagnostic accuracy of RMI and ROMA indices in comparison to HE4 and CA125 parameters for estimating the risk of malignancy of adnexal masses.
Background: Ovarian cancer is the fifth leading cancer-related cause of death in women worldwide and is often diagnosed at advanced stages. Regarding the low sensitivity and specificity of the currently available diagnostic techniques, in the present study, we aimed to evaluate the accuracy of RMI and ROMA indexes and comparing these two indexes with CA-125 and HE4 parameters for the diagnosis ...
متن کاملEvaluation of HE4, CA-125, Risk of Ovarian Malignancy Algorithm (ROMA) and Risk of Malignancy Index (RMI) in the Preoperative Assessment of Patients with Adnexal Mass.
OBJECTIVES To evaluate the validity and compare the performance of cancer antigen-125 (CA-125), human epididymis protein 4 (HE4), the risk of malignancy index (RMI), and the risk of ovarian malignancy algorithm (ROMA) in the diagnosis of ovarian cancer in patients with ovarian lesions discovered during their preoperative work-up investigations. METHODS This prospective, cross-sectional study ...
متن کاملComparing the Diagnostic Value of the Risk of Ovarian Malignancy Algorithm and CA125 in Patients with Ovarian Mass
Background and purpose: Ovarian cancer is the fourth leading cause of death from gynecological cancers in women. Using specific tumor markers that help in making diagnosis at early stages improve therapeutic outcomes. The purpose of this study was to evaluate the diagnostic value of the Risk of Ovarian Malignancy Algorithm (ROMA) index in patients with ovarian mass. Materials and methods: A cr...
متن کاملpreoperative evaluation of risk of ovarian malignancy algorithm index in prediction of malignancy of adnexal masses
results: the only significant difference was the older age of the malignant group vs. benign group (p = 0.001) regarding demographic findings. as concerns the clinical symptoms, presence of abdominal discomfort in pre-diagnosis period was the only significant parameter in malignant group (p = 0.001). additionally, data analysis of patients as a total group showed that specificity (96.4%), posit...
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ژورنال
عنوان ژورنال: Clinics
سال: 2012
ISSN: 1807-5932
DOI: 10.6061/clinics/2012(05)06